{"id":227,"date":"2010-02-04T18:35:23","date_gmt":"2010-02-04T23:35:23","guid":{"rendered":"http:\/\/random-musings.org\/?p=227"},"modified":"2024-11-07T22:32:42","modified_gmt":"2024-11-08T03:32:42","slug":"227","status":"publish","type":"post","link":"https:\/\/random-musings.org\/index.php\/2010\/02\/04\/227\/","title":{"rendered":"Lancet Backtracks"},"content":{"rendered":"\n<p class=\"has-medium-font-size wp-block-paragraph\">In 1998, Andrew Wakefield, MD, published an article in the prestigious British medical journal <em>Lancet<\/em>, allegedly claiming there was a connection between the Measles-Mumps-Rubella (MMR) vaccine for children, and the occurrence of autism.&nbsp; Twelve years later, <em>Lancet<\/em> has retracted this article.<\/p>\n\n\n\n<!--more-->\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">I have long been skeptical of any connection between vaccinations and autism.&nbsp; It would be fairly simple to look back and find it, if it existed.&nbsp; In the so-called developed countries, adequate records are kept that would make it possible to identify a statistical connection.<\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">Dr. Wakefield&#8217;s article may have made such a statistical connection.&nbsp; I don&#8217;t have access to the article, so I can&#8217;t say.&nbsp; Assuming that it did make such a connection, it remained an isolated claim that, to my knowledge, was not verified by other researchers.<\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">As might have been expected, Dr. Wakefield&#8217;s article touched off a furor.\u00a0 The medical profession tended to dismiss the paper.\u00a0 The lay public accepted Dr. Wakefield&#8217;s claim, and hailed him as a courageous dissenter.\u00a0 Millions of parents agonized over whether to get the vaccine; many decided it wasn&#8217;t work the risk.<\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">I&#8217;d never have entertained the possibility that MMR vaccine was related to autism, had <em>Lancet<\/em> not retracted the article.&nbsp; It is common for some research to remain unverified.&nbsp; Mistakes are made all the time.&nbsp; Promising initial results are found not to be confirmed by other researchers.&nbsp; Retractions are rarely made because of this.<\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">Now that <em>Lancet<\/em> has retracted this article, I have to ask myself, &#8220;why?&#8221;&nbsp; Surely this is not the only mistaken article they&#8217;ve published over the years. There must have been dozens, perhaps hundreds of other articles that turned out to be unverified, since Dr. Wakefield&#8217;s. &nbsp; Why was his chosen for retraction, over all the others?&nbsp; What makes his so special?<\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">Could it be that the drug companies &#8220;got&#8221; to <em>Lancet<\/em>, persuading them to retract the article?&nbsp; After all, vaccine sales dropped precipitously when the article came out.&nbsp; Drug companies were hurt &#8211; or at least, their unconscionable profits were slightly decreased.&nbsp; Maybe they &#8220;encouraged&#8221; <em>Lancet<\/em> to retract the article.&nbsp; While this vaccine represented a trivial percentage of total drug profits, the companies may have feared a &#8220;slippery slope&#8221;.&nbsp; If one drug can be criticized, why not others?&nbsp; That could set a bad precedent.<\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">I wonder how much of <em>Lancet&#8217;s<\/em> revenue comes from ads placed by drug companies.&nbsp; If they&#8217;re like other medical publications, their very existence probably relies on these ads.&nbsp; I could not rule out the possibility that <em>Lancet<\/em> caved in to pressure from the drug companies, perhaps threatening to stop advertising in their journal.&nbsp; That would likely be a disaster.<\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">I hasten to add that it is entirely possible that <em>Lancet<\/em> is a wholly ethical, objective publication that cannot be subverted by drug companies or anyone else.&nbsp; <em>Lancet<\/em> is considered one of the most prestigious medical publications in the world &#8211; perhaps <i>the<\/i> most prestigious.&nbsp; They would likely stand firm against pressures that might cause a lesser publication to fold.<\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">The problem isn&#8217;t that we know <em>Lancet<\/em> has been bought.&nbsp; The problem is that we don&#8217;t know that it hasn&#8217;t.&nbsp; How objective can a publication be, when its existence relies upon the same drug companies that are being discussed in the articles?<\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">In many profession, being paid by those you are evaluating is considered a conflict of interests.\u00a0 If Big Oil is paying for research, your results are likely be more favorable to Big Oil, than if Greenpeace is signing your checks.\u00a0\u00a0 If you continue to find flaws with Big Oil, they&#8217;ll stop paying you.<\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">As long as <em>Lancet<\/em> &#8211; and the other medical publications &#8211; survive primarily on ads by pharmaceutical companies, there will remain a serious question of whether these journals are objective.<\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">Update: I have learned that Dr. Wakefield&#8217;s article was not only incorrect, but allegedly fraudulent.&nbsp; That would easily explain why <em>Lancet<\/em> retracted it.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In 1998, Andrew Wakefield, MD, published an article in the prestigious British medical journal Lancet, allegedly claiming there was a connection between the Measles-Mumps-Rubella (MMR) vaccine for children, and the occurrence of autism.&nbsp; Twelve years later, Lancet has retracted this &hellip; <a href=\"https:\/\/random-musings.org\/index.php\/2010\/02\/04\/227\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35,38],"tags":[],"class_list":["post-227","post","type-post","status-publish","format-standard","hentry","category-news","category-science"],"_links":{"self":[{"href":"https:\/\/random-musings.org\/index.php\/wp-json\/wp\/v2\/posts\/227","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/random-musings.org\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/random-musings.org\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/random-musings.org\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/random-musings.org\/index.php\/wp-json\/wp\/v2\/comments?post=227"}],"version-history":[{"count":8,"href":"https:\/\/random-musings.org\/index.php\/wp-json\/wp\/v2\/posts\/227\/revisions"}],"predecessor-version":[{"id":1110,"href":"https:\/\/random-musings.org\/index.php\/wp-json\/wp\/v2\/posts\/227\/revisions\/1110"}],"wp:attachment":[{"href":"https:\/\/random-musings.org\/index.php\/wp-json\/wp\/v2\/media?parent=227"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/random-musings.org\/index.php\/wp-json\/wp\/v2\/categories?post=227"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/random-musings.org\/index.php\/wp-json\/wp\/v2\/tags?post=227"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}